Expression, content, and localization of insulin-like growth factor I in human Achilles tendon

JL Olesen, KM Heinemeier, H Langberg… - Connective tissue …, 2006 - Taylor & Francis
… of tendon tissue, a basic knowledge of its presence in humanhuman Achilles tendons
express IGF-I and IGFBP-4 mRNAs, to describe the localization of IGF-I and IGFBP-4 in the tendon

Expression of insulin-like growth factor I, insulin-like growth factor binding proteins, and collagen mRNA in mechanically loaded plantaris tendon

JL Olesen, KM Heinemeier, F Haddad… - Journal of Applied …, 2006 - journals.physiology.org
… the soleus together with part of the Achilles tendon (5). Sham … -4 has a predominant localization
in connective tissue (10). In … expression appears to be influenced by the loading amount

Differential effects of insulinlike growth factor‐I on matrix and DNA synthesis in various regions and types of rabbit tendons

SO Abrahamsson, S Lohmander - Journal of orthopaedic …, 1996 - Wiley Online Library
… deep flexor tendons of the hindpaws and the two Achilles tendons of … and Achilles (Ach)
tendons after short-term culture in … HJ: Localization of somatomedin-C binding to bovine growth-…

Insulinlike growth factor‐I is expressed by avian flexor tendon cells

M Tsuzaki, BE Brigman, J Yamamoto… - Journal of …, 2000 - Wiley Online Library
… in dynamically loaded rat Achilles tendons, indicating that cyclic load … location may support
tendon cell migration and DNA synthesis and division and then stimulate matrix expression

Insulinlike growth factor‐I improves cellular and molecular aspects of healing in a collagenase‐induced model of flexor tendinitis

LA Dahlgren, MCH van der Meulen… - Journal of …, 2002 - Wiley Online Library
… The Achilles tendon, patellar tendon, and rotator cuff of the … Localization of mRNA by in
situ hybridization was used to eval… Long-term explant culture of rabbit flexor tendon: effects of …

[HTML][HTML] Insulin-like growth factor 1 signaling in tenocytes is required for adult tendon growth

NP Disser, KB Sugg, JR Talarek, DC Sarver… - The FASEB …, 2019 - ncbi.nlm.nih.gov
expression of Col1a1 and Col1a2 in whole tendons, and the … , in which the Achilles tendon
is surgically removed resulting … This causes the localization of PI3K to the plasma membrane …

Tenocyte responses to mechanical loading in vivo: a role for local insulinlike growth factor 1 signaling in early tendinosis in rats

A Scott, JL Cook, DA Hart, DC Walker… - Arthritis & …, 2007 - Wiley Online Library
Insulin-like growth factor 1 (IGF-1) expression was determined … Both the amount and the
location of IRS-1 phosphorylation … R 2 = 0.4864, P = 0.003) expression, suggesting that the IGF-1 …

[HTML][HTML] Insulin-like growth factor binding protein 4 loaded electrospun membrane ameliorating tendon injury by promoting retention of IGF-1

H Wang, R Yu, M Wang, S Wang, X Ouyang… - Journal of Controlled …, 2023 - Elsevier
… the IGFBPs, is expressed in human Achilles tendon [12,13]. … membrane increased the content
of tendon-related markers (… demonstrated location around human tendon fibroblasts [12]. …

Insulin-like growth factor I accelerates functional recovery from Achilles tendon injury in a rat model

CA Kurtz, TG Loebig, DD Anderson… - … American journal of …, 1999 - journals.sagepub.com
… We studied the effects of insulin-like growth factor I on Achilles tendon healing in a rat model…
, and transection plus growth factor. Postoperatively, rats treated with growth factor had a …

… of local administration of insulin-like growth factor-1 in addition to heavy slow resistance training in tendinopathic human patellar tendons: A randomized, double-blind …

JL Olesen, M Hansen… - … American Journal of …, 2021 - journals.sagepub.com
… tenderness localized to the inferior pole of the patellar tendonexpression in the tendon to
the same extent as a tendon … of the tendon relative to the healthy region of the Achilles tendon. …